“If there’s a beginning, there must be an end,” Zendaya’s character, Rue, says in the penultimate episode of Euphoria season three, which ends, likely for good, with its May 31 finale.

The hit teen drama premiered on HBO in the summer of 2019, back when “Old Town Road” topped the charts and the biggest thing Jacob Elordi had ever done was kiss Joey King at a carnival. Seven years and merely three seasons later, Euphoria has become part of the zeitgeist, remembered for its bedazzled underage debauchery as well as its provocative commentary on coming of age in Trump’s America. Euphoria launched Zendaya and now Oscar nominee Elordi into the stratosphere, alongside costars Hunter Schafer, Maude Apatow, Alexa Demie, and Sydney Sweeney.

Fate has been less favorable to their onscreen counterparts, who, five years after graduating East Highland High School, are all going through it. Rue descends into crime, working with Nazis, the feds, and a Black cowboy in a drug plot that stems from her adolescent foibles with monotone drug dealer Laurie (Martha Kelly). Cassie (Sweeney) and Maddy (Demie) both hit bumps in pursuing their show business dreams: Cassie loses a role on LA Nights (the TV show on which sister, Lexi, played by Apatow, writes) due to her OnlyFans account. Meanwhile, Maddy gets fired from her assistant job in part for helping Cassie escape her toxic marriage to Nate. Maddy negotiates with strip club owner Alamo (Adewale Akinnuoye-Agbaje) to pay off Nate’s debts, but nothing can save her ex from his destiny: being buried alive on one of his own construction sites, the parts of him that haven’t been removed with garden shears poisoned by a rattlesnake.

There’s a lot of plot for a show that also insists on confining Jules (Schafer) to a high-rise apartment, where she waits by an easel for a mysterious sugar daddy…all season long. I hope Jules gets more to do in the Euphoria finale, which should give proper send-offs to all its remaining characters.

Below, seven VF staffers share their predictions for what will happen as Euphoria comes to a dramatic close. Possible spoilers to follow—assuming we made good on our guesses.