We’ve had the technology for nuclear power generation since the 1950s but aside from France, every country has continued to favor oil, natural gas, and coal since then. That’s changing though.

Around the world, nuclear power is enjoying a renaissance of renewed interest and investment. In the U.S. alone, the Department of Energy has set a goal to triple America’s nuclear output by the middle of the century. Big tech companies are working with power companies to resurrect nuclear plants to power data centers.

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As a result of that interest, nuclear stocks have been surging. And these three appear to be some of the best.

Image source: Getty Images.

Up first is Cameco (NYSE: CCJ), one of the world’s premier uranium miners. In 2025, it was responsible for 15% of all the uranium produced in the world that year. The only company that produced more was Kazakhstan’s state-owned company Kazatomprom.

The company is present through virtually the entirety of the nuclear fuel cycle. It has two high-grade mines in Canada and a third low-grade mine in Kazakhstan. It also has a fuel services division that refines and produces finished uranium fuel rods.

Finally, through a joint venture with Brookfield Asset Management (NYSE: BAM) it has 49% ownership of Westinghouse, an engineering company that produces the AP1000, which is the most advanced nuclear reactor on the market today.

For 2025, Cameco’s revenue grew 11% and it maintains both a high net profit margin of 16.9% and a low debt-to-equity ratio of 0.14, which is good to see in an industry as capital intensive as mining.

All the uranium Cameco mines is for reactors around the world, including the 94 in the United States. And the single largest operator of those nuclear reactors is Constellation Energy Corp (NASDAQ: CEG).

Constellation is a pretty straightforward energy company with one key thing that sets it apart. It’s both America’s largest producer of green energy and its largest producer of nuclear energy. It owns 21 of America’s nuclear reactors and it will be adding a new one soon.

The company has partnered with Microsoft (NASDAQ: MSFT) to recomission part of the Three Mile Island nuclear plant as the Crane Clean Energy Center. Once completed (targeted for 2028), Microsoft has a 20-year power purchase agreement with Constellation to buy energy from the plant for its data centers in the area.

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